BDBM29744 hydroxyethylene tripeptide inhibitor, 1

SMILES CCCCNC(=O)[C@H](C)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@H](CCSC)NC(=O)CCC(C)C

InChI Key InChIKey=XTRMRNMVFXWTCC-MLNNCEHLSA-N

Data  5 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 29744   

TargetCathepsin D(Homo sapiens (Human))
Novartis

LigandPNGBDBM29744(hydroxyethylene tripeptide inhibitor, 1)
Affinity DataIC50:  370nMpH: 3.1 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Novartis

LigandPNGBDBM29744(hydroxyethylene tripeptide inhibitor, 1)
Affinity DataIC50:  370nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed